Dr. R.Shakila
Academic Qualification: M.Sc., M.Phil., Ph.D.
Specialization: Analytical chemistry, Phytochemistry, Instrumentation (HPTLC/HPLC/PXRD)
Additional Qualification:
Diploma in Factory Law Management
Personal Details:
Marital Status: Married
Date of Birth: 21/06/1973
Date of Joining: 19/12/2010
Research Experience & Area of Specialisation
- 22 years of research experience in
standardization of ISM drugs.
- Analytical chemistry, Phytochemistry, Instrumentation (HPTLC/HPLC/PXRD).
Projects
Current Project:
To develop Pharmacopoeia monographs on single drugs of plant origin sponsored by PCIM & H.
Completed Projects:
Intramural Research Project:-
Isolation of chemical marker from selected plants used in Reproductive and child Health.
2.Analysis of Inorganic composition of Selected plants used in Siddha system.
Extramural Research Project :-
To develop pharmacopoeial monographs on Standard Operational Procedures (SOPs) of manufacturing processes and quality standards of Ayurveda/ Siddha/ Unani/ Homoeopathy (ASU&H) formulations (including stability studies) sponsored by PCIM & H.
Publications
Web of Science (SCIE) Indexed Journals
- Sujith T, Murugammal S, Shakila R , Gopinath P. Screening of lupeol, lupeol acetate, β-sitosterol, ρ-coumaric acid and protocatechuic acid in Hemidesmus indicus (L.) R.Br. & Decalepis hamiltonii Wight & Arn. followed by quantification using HPTLC for quality assessment. Journal of Applied Research on Medicinal and Aromatic Plants. 2023; https://doi.org/10.1016/j.jarmap.2023.100510. Scopus IF: 3.9.
- Thanalakshmi J, Archana, Senthilkumar S, Shakila R , Pazhanivel N, Subhashini S. Role of caloric vestibular stimulation in improvement of motor symptoms and inhibition of neuronal degeneration in rotenone model of Parkinson's disease – An experimental study. Physiol Int. 2020; 107(3): 390-405. DOI: https://doi.org/10.1556/2060.2020.00036. IF: 1.697
- Subashini S, Raju K, Sujith T, Shyamala R, Shakila R.Differentiation of Market Samples of Chennai Nagakesara and Nagakesara by Chromatographic Techniques. Indian J Pharmaceut Sci 2021; 83 (4), 775-84. DOI: 10.36468/pharmaceutical-sciences.829. IF 0.5
- Sunilkumar KN, Shakila R , Balakrishna K, Amerjothi S. Phytochemical examination of compounds from Mango mistletoe - Helicanthus elastica (Desr.) Danser. Indian J Chem Sec B. 2015; 54B(7): 924-929. Scopus IF: 0.5.
- 5. A. Saraswathy, R. Shakila , Mercy Lavanya S, A. Arunmozhi Devi. Volatile constituents of Illicium griffithii Hook f. et. fruit and its antimicrobial activity. Phcog Mag. 2010; 2(23): 208-211. DOI: 10.4103/0973-1296.66938. PMCID: PMC2950384. IF: 0.5
Web of Science (ESCI) Indexed Journals
- Brinda S, Mandal AK, Vinayak S, Shree Devi MS, Sunil Kumar KN, Shakila R , Sathiyarajeswaran P, Kiruthiga G. Standardization of Kirāmpu Kutinīr Decoction and Extract Granules using pharmacognostic, physicochemical and HPTLC Studies. Int J Pharm Investigation 2021; 11(4): 1-6. DOI: 10.5530/ijpi.2021.3.52. IF: 0.5.
- Mandal AK, Shakila R, Thatipelli S, Rubeena M, Sunilkumar KN, Thilagam A, Ganesan R. Quality Standards and Anti-oxidant Activity of Siddha Formulation Cuvacakutori Chooranam. Int. J. Pharm. Investigation. 2019; 9(3): 128-34. DOI: 10.5330/ijpi.2019.3.24. IF: 0.5.
- Susikumar S, Gokula Kannan S, Achintya Kumar Mandal, Shakila R , Sunil Kumar KN, Senthilvel G. Macro-microscopic and HPTLC Atlas of Canavalia gladiata (Jacq.) DC. Fruit. Phcog Res. 2023; 15(2): 277-287. DOI:10.5530/pres.15.2.030. IF:0.7
- Sujith T, Susikumar S, Sunilkumar KN, Radha P, Shakila R , Gopinath P. Detection of adulteration of Decalepis hamiltonii Wight & Arn. With Hemidesmus indicus (L.) R. Br. by pharmacognostic, molecular DNA fingerprinting by RAPD, chemical and HPTLC studies. Plant Science Today. 2021; 8(3): 610–620. https://doi.org/10.14719/pst.2021.8.3.1151. IF: 0.9.
- Mandal A K, Sujith T, Rajesh A, Divya KG, Sunilkumar KN, Shakila R . Powdermicroscopic, physicochemical and chromatographic approach for the quality control of anti-hypertensive drug Rattha Piththathirku Kudinir Chooranam. Plant Science Today. 2021; 8(3): 604–609. https://doi.org/10.14719/pst.2021.8.2.1137. IF: 0.9.
- Brindha S, Remya A, Divya KG, Rubeena M, Erni B, Murugammal S, ShakilaR , Sunilkumar KN. Key distinguishing characters (KDCs) of official (Boerhaavia diffusa L.) and commonly mistaken (Trianthema portulacastrum L.) sources of Mukkirattai of Siddha. Plant Science Today. 2020; 7(3): 391-403. DOI: https://doi.org/10.14719/pst.2020.7.3.792. IF: 0.9.
- Radha P, Divya KG, Udhayavani C, Murugammal S, Shakila R , Sunil Kumar KN. Morpho-anatomy and HPTLC profiling of Senna Mill. seeds used in traditional system of Indian medicine. Pharmacogn. Res. 2023; 15(3): 551-561. DOI: 10.5530/pres.15.3.058. IF:0.7.
- Mandal AK, Divya KG, Habeebmon KC, Sunil Kumar KN, Shakila R . Fingerprints of two medicinal species of Alternanthera – A. ficoidea and A. sessilis to facilitate differentiation in dried form. Indian J Nat Prod Resour. 2022; 13(4): 525-536. DOI: 10.56042/ijnpr.v13i4.58016. Scopus IF:0.8.
- Mandal AK, Shakila R. Pharmacopoeial Standards for Venpucani Ilakam - a classical Siddha medicine.Int J Ayur Med. 2022; 13(4): 939-943. IF: 0.2
- Susikumar S, Sunil Kumar KN,Madhavraj V, Shakila R, Sekar T, Ilavarasan R. Macro-microscopy and HPTLC Atlas of Heartwood of Erythroxylum monogynum Roxb. (Indian Bastard Sandalwood). Pharmacog Res. 2023; 15(1): 176-183. DOI:10.5530/097484900201. IF:0.7
- Rajesh A, Padmini D, Indumathi M, Sujith T, Mandal AK, Ganesan R, Shakila R. Antimicrobial activity and Quality Control Parameters of Taḷicati Vatakam - a Classical Siddha Drug. Int J Ayur Med. 2022;13(2): 463-468. IF: 0.2
- Shakila R , Saravanan M, Subashini S, Sujith T, Mandal AK, Rajesh A. Development of chromatographic fingerprint profile and multielemental analysis of Datura metel L. Pharmacog Res. 2022; 14(2): 146-152. DOI: 10.5530/pres.14.2.21. IF:0.7
- Sujith T, Mandal AK, Shakila R. Chemical Standards and HPTLC Finger Print Profiles of a Siddha Polyherbal Formulation- Kadukkai Legiyam. Int J Ayur Med. 2021; 12(4): 922-926. IF: 0.2.
- Mandal AK, Saravanan M, Subashini S, Sujith T, Rajesh A, Shakila R. Characterization of Solanum surattense Burm.f fruit through chromatographic, chemical and analytical methods. J Young Pharm 2021; 13(4): 370-374. DOI: 10.5530/jyp.2017.9.95. IF: 0.4.
- Sujith T, Shakila R , Mandal AK, Divya KG, Mahesh F, Sunilkumar KN, Ganesan R. Powder Microscopic, Physicochemical, HPTLC and Antioxidant Studies on Noccik Kudinir Chooranam – A Polyherbal Siddha Formulation. J Young Pharm. 2019; 11(4): 371-6. DOI:10.5530/jyp.2019.11.76. IF: 0.4.
- Murugammal S, Gandhi MR, Pandikumar P, Shakila R,Ilavarasan R. Lactivity of Epaltes pygmaea (DC) whole plant extracts against Culex quinquefasciatus Say, Aedes aegypti L. and Anopheles stephensi Liston larvae. Int J Pharmaceut Sci Res. 2020; 11(3): 1296-8. DOI: 10.13040/IJPSR.0975-8232.11(3).1296-98.
- Akila B, Manickavasakam K, Shakila R . Pharmacognostical and physicochemical studies on Adhatoda vasica Nees seed. Int J Pharmaceut Sci Res 2014; 5(12): 1000-1009.
Scopus Indexed Journals
- Murugammal S, Subashini S, Shakila R . Method development and validation for quantification of six bioactive compounds (andrographolide, columbin, gallic acid, ρ-coumaric acid, piperine and oleanolic acid) by High Performance Thin Layer Chromatography. J Complement Integr Med. 2022; https://doi.org/10.1515/jcim-2022-0135. PMID: 36384045 IF: 1.824.
- Shakila R , Saravanan M, Rajesh A, Sujith T, Mandal AK. Proximate analysis, HPTLC finger print analysis and Multi Spectrometric analysis of Strychnos nux-vomica nuts. J Complement Integr Med. 2021; https://doi.org/10.1515/jcim-2021-0528. PMID: 34957732 IF: 1.824.
- Sushanth NK, Vijayalakshmi S, Dayanand Reddy G, Sunil Kumar KN, Shakila R . Protective effect of hydro alcoholic extract of Aloe vera supplemented by zinc on the testis of wistar albino rats exposed to cadmium. Int. J. Res. Pharm. Sci., 2020; 11 (SPL4):2128-2133. DOI: https://doi.org/10.26452/ijrps.v11iSPL4.4431
- Sivaranjani K, Shakila R , Manickavasakam K. Standardisation of Siddha Polyherbal Formulation Parangipattai chooranam. Int J Res Ayurveda Pharm 2015; 6(4): 443-448. DOI: 10.7897/2277-4343.06485.
- Subashini, R. Shakila . Identification of phytoconstituents of Cirunakappu by gas chromatography– mass spectrometry. Int J Green Pharm. 2020; 14(3): 274-279. DOI: http://dx.doi.org/10.22377/ijgp.v14i03.2941.
- Murugammal S, Meeradevi Sri P, Shakila R, Ilavarasan R. Exploration of antibacterial activity of various extracts of Epaltes pygmaea DC. against few bacterial organisms. Int J Res Ayurveda Pharm. 2018; 9(2):52-56. DOI: 10.7897/2277-4343.09235.
- Sunilkumar KN, Shakila R , Amerjothy S. Physicochemical evaluation, nutraceutical composition and HPLC‑UV fingerprint of Helicanthus elastica (Desr.) Danser (Indian Mango Mistletoe). Int J Green Pharm 2014; 8(3): 175-179.DOI: http://dx.doi.org/10.22377/ijgp.v8i3.381.
- Elankani P, Murugammal S, Shakila R , Pitchiahkumar M, Kabilan N. Chemical Standardization of Thetran Vithai Kutinir Chooranam - An Antidiabetic Siddha Polyherbal Formulation. Pharmacog J. 2019; 11(5): 1106-13. DOI: 10.5530/pj.2019.11.173
- Mandal AK, Shakila R , Divya KG, Rubeena M, Sunil Kumar KN, Sathiyarajeswaran P. Pharmacognostical-physico-chemical Evaluation and Development of HPTLC Finger print for Cichorium intybus L. fruits. Pharmacog J. 2017; 10(4): 694-699. DOI :10.5530/pj.2018.4.115
- Shakila R . Review on Sphaeranthus indicus Linn. (Koṭṭaikkarantai). Phcog Rev . 2013; 7(14): 157-169. DOI: 10.4103/0973-7847.120517. PMCID: PMC3841994.
- Saraswathi A, Sunil Kumar KN, Shakila R , Ariyanathan S. Pharmacopoeial standards for roots of Cocos nucifera Linn. Phcog J. 2010; 2(12): 498-501. https://doi.org/10.1016/S0975-3575(10)80038-0.
- A.Saraswathi, A.K.Meena, R.Shakila , K.N.Sunil Kumar, S.Ariyanathan. Standardisation studies on Alangium salvifolium (Linn.f.) Wang. root bark. Phcog J. 2010; 2(11): 374-380. https://doi.org/10.1016/S0975-3575(10)80018-5.
- A.Saraswathy, R. Shakila , K.N.Sunil Kumar. HPTLC finger print profile of some Cinnamomum species. Phcog J. 2010; 2(7): 211-215. https://doi.org/10.1016/S0975-3575(10)80095-1.
Other Peer Reviewed Journals
- R.Ganesan, R.Nithya, B.Nandhini, R.Shakila , A.Rajesh, F. Mahesh P.Sathiya Rajeswaran. Phytochemical analysis of siddha polyherbal formulation Arathai Kudineer Churnam. Journal of Pharmacognosy and Phytochemistry. 2018; 7(6): 2467-2470.
- S. Murugammal, R.Shakila , R. Ilavarasan. Identification of Phyto constituents and Development of TLC and HPTLC finger print profiles for Epaltes pygmaea DC. Int. Res. J. Pharm . 2019; 10(10):109-114. DOI: 10.7897/2230-8407.1010308
- KG. Divya, M. Rubeena, A. Remya, B. Erni, S. Brindha, T. Sujith, K N. Sunil Kumar, R. Shakila. Identity profile of Moringa oleifera Lam. Flower. Int. J Bot Studies . 2019; 4(4): 90-99.
- Shakila R, Arul Antony S, Gopakumar K. Lipid Composition of Desmostachya bipinnata rootstock. Der Chemica Sinica 2014; 5(5): 47-51. IF: 0.676.
- A.Saraswathy, K. Amala, R. Shakila , K.N.Sunil Kumar. Pharmacognostic and Preliminary phytochemical studies on the stem of Terminalia alata Heyne ex Roth. JMAPS . 2009: 31(1): 42-47.
- Shakila R , Arul Antony S, Sathiyarajeswaran P. Chemical standardization of Desmostachya bipinnata (linn.) stapf. Rootstock. European Journal of Biomedical and Pharmaceutical Sciences . 2016: 3(10): 387.
- Lakshmikantham T, Ganapathy G, Shakila R, Geetha A, Banumathy A. Standardization of Nandhi Mezhugu, a poly herbomineral Siddha formulation. Journal of Pharmacy Research. 2016: 10(10); 666-673.
- ShakilaR , Ganesan R, Meeradevi Sri P, Arul Antony S, Sathiyarajeswaran P. Antimicrobial studies of Coldenia procumbens Linn. whole plant. World Journal of Pharmaceutical Sciences. 2017; 5(4): 25-27.
- Meena S, Kaniraja S, Shakila R, Shree Devi MS, Sathiya Rajeswaran P.Standardization of a polyherbal formulation Vajravalli Chooranam. Int J Pharm Tech Res. 2016; 9(6): 191-99.
- R. Shakila , R Jayachandran, Shyamala Rajkumar, A. Kanagarajan, P Sathiyarajeswaran. Chemical Standardization of Mucamparap Parru. International Journal of Pharmacognosy. 2016; 3(1): 35-42. DOI: 10.13040/IJPSR.0975-8232.IJP.3(1).35-42
- Anitha John, Sasikala E, Jayachandran R, Shakila R , Sathiyarajeswaran P. Standardization of Chuntaivatral chooranam – a polyherbal siddha formulation. European Journal of Pharmaceutical and Medical Research 2015; 2(7): 156-160.
- Jayasree D, Shakila R , Meeradevi Sri P. Evaluation of antibacterial activity of ethanolic extract of Butea monosperma (Lam.) Kuntz pod. J Pharmaceut Chem Biol Sci 2015; 3(1): 01-05.
- Sariga CD, Shakila R , Kothai S. Isolation, characterization and quantification of bergenin from Syzygium cumini stem bark. International Research Journal of Pharmacy. 2015; 6(2): 108-110.
- Chitra B, Ramaswamy RS, Shakila R . Characterization of a siddha drug (Pũrṇa Cantirotaya Centũram): an approach to standardization. Int J Pharm Bio Sci 2015; 6(1): (P) 567-577.
- Shakila R, Arul Antony S, Gopakumar K. Phytochemical studies on Desmostachyabipinnata rootstock. Int J Pharm Bio Sci 2015; 6(1): (P) 305-310.
- Aarthi V, Shakila R , Sasikala E, Pitchiahkumar M. Pharmacognostical studies on Ehretia microphylla Lamk. Asian Journal of Traditional Medicine 2014; 9(5): 118-129.
- Lavanya A, ShakilaR , Sasikala E, Ayyasamy S. Pharmacognostical studies on the leaves of Canavalia virosa (Roxb.) Wight & Arn. Asian Journal of Traditional Medicine. 2014; 9(1): 8-17.
- Shakila R, Meeradevi Sri P, Arul Antony S, Gopakumar K.Antimicrobial Studies on Desmostachyabipinnata rootstock.J Pharmaceut Chem Biol Sci 2014; 2(3): 197-201.
- Akila B, Manickavasakam K, Shakila R . Analytical study on siddha herbomineral formulation: Chandrakanthi chooranam. Int J Pharm Bio Sci 2014; Oct 5(4): (P) 175 – 185.
- Akila B, Manickavasakam K, Shakila R.Chemical Analysis of Gomutra Silasathu Parpam. Int J Drug Delivery 2014; 6(1): 88-93.
- Shakila R, Elankani P, Jegajothipandian S. Development of finger print profiles for Androgrphis echioides Nees. and Andrographis paniculata Nees. Research Journal of Pharmacognosy and Phytochemistry. 2014; 6(1): 22-29.
- Priya F, Shakila R , Sathiyarajeswaran P, Pitchiahkumar M. Standardization of Milagathi Choornam. International J Herbal Medicine. 2014; 1(6): 69-74.
- Shakila R . Chromatographic studies on Artemisia nilagiria Leaf Volatile oil. Asian J Pharm Life Sci. 2013; 3(3): 185-190.
- A. Saraswathy, K. Amala, R. Shakila , N.S. Hema Kumar. Pharmacognostic, physico-chemical and preliminary phytochemical studies on stem bark of Caesalpinia coriaria (Jacq.) Willd. J Pharm Res.2011; 4(6): 1666-9.
- Saraswathy A, Shakila R. Quantitative estimation of geranial and luteolin from Cymbopogon citratus (DC.) Stapf. leaf using high performance thin layer chromatography. Indian Drugs 2008; 45(8): 663-666.
- Saraswathy A, Joy S, Shakila R. Quantification of tamarindienal from Tamarindus indica Linn. fruit using high performance thin layer chromatography. Indian Drugs 2007; 44(5): 398-400.
Book Publications
81 monographs which are published in the book series of “ Quality Standards of Indian Medicinal Plants (QSIMP) ”, Vol. 5-14, published by Indian Council of Medical Research , New Delhi.
Monograph on Ayush Kudinir Chooranam published by PCIM
Chapter In Book K Santhiya-Nair, P Logeiswariy, S Sreeramanan, R Shakila, Y Chen, YH Leong, S Karupiah, S Sasidharan. Purification of herbal biomolecules. In: Herbal Biomolecules in Healthcare Applications. Cambridge, Massachusetts: Academic Press: 2022, p47-62. https://doi.org/10.1016/B978-0-323-85852-6.00010-X